Hanqing Liu

Time2015-12-24 Onclick

Hanqing Liu

Ph.D.

Jiangsu Specially-Appointed Professor

Department of Pharmaceutics, School of Pharmacy

CONTACT INFORMATION

Room 2207, School of Pharmacy

Jiangsu University

301 Xuefu Road, Jingkou District, Zhenjiang, Jiangsu 212013

Email: hanqing@ujs.edu.cn

EDUCATION AND TRAINING

Oct 2013-Date School of Pharmacy Jiangsu University Zhenjiang, China

Nov 2010-Oct 2013 Postdoctoral Fellow, Developmental Therapeutics Fox Chase Cancer Center Philadelphia, U.S.

Dec 2010 Ph.D. Biochemistry University of Pennsylvania Philadelphia, U.S.

July 2004 M.S.Analytical ChemistryShanghai Institute of Organic Chemistry, Chinese Academy of Sciences (SIOC) Shanghai, China

July 2001 B.S.BiopharmaceuticsNanjing University & China Pharmaceutical University Nanjing, China

RESEARCH INTERESTS

Targeted therapy in cancers; understanding drug resistance networks in ovarian cancer; Identifying and Targeting Signaling Hubs in Cancer synthetic lethality screens in cancers

FUNDINGS AS PI

Senior talent start-up funds, Jiangsu University

Jiangsu Specially-Appointed Professor Award, Jiangsu Province, Dec 2013-Dec 2016

Ann Schreiber Program of Excellence Award,Ovarian Cancer Research Fund, Jul 2012-Oct 2013

Postdoctoral Fellowship, SASS Foundation for Medical Research, Jul 2011-Jun 2012

RECENT PUBLICATIONS

JOURNAL PAPERS

1.Hanqing Liu, Fang Xiao, Ilya G. Serebriiskiia, Shane OBrien, Marisa Maglaty, David Proia, Erica A. Golemis, Denise C. Connolly. Network analysis identifies an HSP90-central hub susceptible in ovarian cancer.Clin Cancer Res.2013, 19(18):5053-67 (IF=7.8

2.Hanqing Liu, Chunlai Chen, Haibo Zhang, Jaskiran Kaur, Yale E. Goldman, and Barry S. Cooperman. EF4 (LepA) Modulates the Elongation Cycle of Protein Synthesis.Proc Natl Acad Sci U S A2011, 108(39),16223-16228 (IF=9.7

3. Aleksandra Mikolajka#,Hanqing Liu#,Yuanwei Chen, Agata L. Starosta, Viter Mrquez, Barry S. Cooperman, Daniel Wilson. Differential effects of thiopeptide and orthosomycin antibiotics on translational GTPases.Chemistry& Biology2011, 18(5), 589-600 (IF=6.2(co-first author)

4. Cuiping Liu, Howard Gamper,Hanqing Liu, Barry S. Cooperman, and Ya-Ming Hou. Potential for interdependent development of tRNA determinants for aminoacylation and ribosome decoding.Nature Communication2011, 2, 329 (IF=10.0)

5. Chunlai Chen, Benjamin Stevens, Jaskarin Kaur, Diana Cabral,Hanqing Liu, Yuhong Wang, Haibo Zhang, Gabriel Rosenblum, Zeev Smilansky, Yale E. Goldman, Barry S. Cooperman. Single Molecule Fluorescence Measurements of Ribosomal Translocation Dynamics.Molecular Cell2011, 42(3), 367-77 (IF=15.3)

6.Hanqing Liu, Dongli Pan, Markus Pech, Barry S. Cooperman. Interrupted Catalysis: The EF4 (LepA) Effect on Back Translocation.Journal of Molecular Biology2010, 396(4), 1043-52 (IF=3.9)

7. Thu Betteridge#,Hanqing Liu#, Howard Gamper, Stanislav Kirillov, Barry S. Cooperman, and Ya-Ming Hou. A General Approach for Fluorescent Labeling of tRNAs.RNA, 2007,13(9), 1594-1601 (IF=6.0(co-first author)

BOOK CHAPTERS

1.Hanqing Liu, Jennifer R. Cracchiolob, Tim M. Beck, Ilya G. Serebriiskiia, and Erica A. Golemis (2014). EGFR Inhibitors as Therapeutic Agents in Head and Neck Cancer. In Molecular Determinants of Head and Neck Cancer Incidence and Prognosis, Barbara Burtness, Erica A. Golemis, eds. (Springer Press) (in press)

2.Hanqing Liu, Tim M. Beck, Erica A. Golemis, and Ilya G. Serebriiskii (2013). Integrating In Silico Resources to Map a Signaling Network. Methods Mol Biol. 1101:197-245, 2014

3. Barry S. Cooperman, Yale E. Goldman, Chunlai Chen, Ian Farrell, Jaskarin Kaur,Hanqing Liu, Wei Liu, Gabriel Rosenblum, Zeev Smilansky, Benjamin Stevens, and Haibo Zhang, (2011). Mechanism and dynamics of the elongation cycle. In Ribosomes: Structure, Function and Dynamics, Marina Rodnina, Wolfgang Wintermeyer, Rachel Green, eds. (Springer Press) pp339-348

4. Yinlong Guo,Hanqing Liu, Chongtian Yu. Applications of Biological Mass Spectrometry on Studies of Noncovalent Interactions of Biological Molecules. In: Applications of Organic Mass Spectrometry on Life Sciences and Medicines. (Songcheng Yang, ed.), Beijing: Chemical Industry Press, pp. 37-59, 2009.

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